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& MacDonald, P

Okadaic acid Okadaic Acid (OA) is a marine toxin produced by certain types of dinoflagellates, and it is well-known for its inhibitory effect on protein phosphatases, particularly protein phosphatase 1 and protein phosphatase 2A

Similarly, 1,25(OH) 2 D 3 , astaxanthin, and echinatin can become resistant to ferroptosis by increasing GPX4 level (Cheng et al., 2021

Its safety profile is generally favorable, but several specific considerations deserve clinician attention particularly around copper biology, zinc balance, and the small number of patient populations where caution or contraindication applies