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Dark Spots on Nails What Is Melanonychia Introduction: Melanonychia is a condition characterized by dark pigmentation or discoloration of the nails, typically affecting one or more nails

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On the other hand, the transcription factor Nrf2 (NF-E2 p45-related factor 2) regulates the expression of anti-inflammatory and antioxidant NADPH, NAD(P)H quinone oxidoreductase 1, glutathione peroxidase, ferritin, hemeoxygenase-1 (HO-1) and other detoxifying enzyme genes