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Q357 forms a hydrogen bond with the cysteine part, enhancing the stability of the middle part of the ligand

GLP 1RAs treatment, source: reference [1] Semaglutide Reduces Cardiovascular Disease Risk As obesity is an important risk factor for cardiovascular disease, weight loss should theoretically reduce the risk of cardiovascular disease in participants, however, this speculation has not been validated by clinical trials

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Pericytes of the neurovascular unit: key functions and signaling pathways