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The liver is the bodys primary detoxification organ, responsible for filtering toxins from the blood and metabolizing drugs and other substances
1, Extended Data Tables 16 and Supplementary Section 2), with a clear trend of growing relevant literature over the past few years as the use of these medications becomes more widespread and their indications expand far beyond the initial intentions of the manufacturers 223
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This leads to a reduction in ATP production and, therefore, an increase in the level of AMP and as a result activation of AMPK
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