(PubMed) Miyake A, Friedman NP, Emerson MJ, Witzki AH, Howerter A, Wager TD
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
Major barriers to the clinical use of gene therapy, however, include transfection efficiency, the creation of long-term effects, the difficulty of controlling cell proliferation, ectopic transfection, disease transmission, patient-specific dose responses, immune reactions against viral proteins, possible side effects, and ethical issues [87, 88]
Supplied reagents are in solution and require simple dilution for use in the assay