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Indications: Preanesthetic medication : to prevent or reduce secretions of the respiratory tract that occur during surgery where general anesthetics are used To restore cardiac rate and arterial blood pressure during anesthesia when vagal stimulation produced by intra-abdominal surgical traction causes a sudden decrease in pulse rate and cardiac output

RSL3 (MedChemExpress, HY-100218A) was dissolved in 10% DMSO and 90% 20% SBE--CD in saline and was administered i.p

Nonetheless, it should be emphasized that both mentioned therapeutic approaches are currently considered off label

Further experiments to clarify this point gave surprising results