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Given the heightened presence of volatile sulfur compounds in ripe durian pulp 28 , known for their contributions to the unpleasant roasty and onion-like odor 36 , our primary objective in this investigation was to explore the protective effects of UDE containing no volatile sulfur compounds against oxidative stress-induced neurotoxicity and neuroinflammation in human cells

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Key points The weight loss induced by glucagon-like peptide receptor 1 agonists (GLP1RAs) should reduce the risk of some malignancies, although stimulation of GLP1 receptors might have either detrimental or beneficial direct effects on cancer risk

Real-world results are often lower than clinical trials for both, largely due to the challenge of staying on the medication long-term