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Conclusion: Altogether, our results show that the cellular antioxidant defense systems contribute to leukemia resistance to MTX, and targeting these pathways, especially the thioredoxin antioxidant system, may be a promising strategy for resensitizing ALL to MTX

At 6 weeks post-operation, better graft incorporation at the tibial tunnel was observed in the 0.3 mg/ml GHK-Cu group, though this difference did not reach statistical significance

Understanding Glutathione's Sensitivity Glutathione is a tripeptide composed of glutamic acid, cysteine, and glycine

Consistent application shows visible improvement within 4-6 weeks