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These may include: Injection site redness or tenderness Mild headaches or dizziness Nausea or digestive discomfort Temporary joint or muscle soreness Water retention (CJC) Histamine response: flushing, tingling, redness (CJC) Mild fever or chills (Thymosin Alpha-1) If symptoms persist or become uncomfortable, contact our Denver office before taking your next dose

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Tocilizumab as monotherapy or combination therapy for treating active rheumatoid arthritis: a meta-analysis of efficacy and safety reported in randomized controlled trials