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[1] Fungi, plants and animals (including humans) cannot produce vitamin B 12

Researchers are investigating it as a potential treatment for stroke and other brain problems involving free radical damage, such as dementia and because ALA can pass easily into the brain, it may help protect the brain and nerve tissue

Persani L, Cools M, Ioakim S, Faisal Ahmed S, Andonova S, Avbelj-Stefanija M, Baronio F, Bouligand J, Bruggenwirth HT, Davies JH, De Baere E, Dzivite-Krisane I, Fernandez-Alvarez P, Gheldof A, Giavoli C, Gravholt CH, Hiort O, Holterhus P, Juul A, Krausz C, Lagerstedt-Robinson K, McGowan R, Neumann U, Novelli A, Peyrassol X, Phylactou LA, Rohayem J, Touraine P, Westra D, Vezzoli V, Rossetti R (2022) The genetic diagnosis of rare endocrine disorders of sex development and maturation: a survey among Endo-ERN centres

Canadians report this combination offers a comprehensive approach to metabolic health that neither compound achieves alone