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Initiation of XIGDUO XR is not recommended in patients with an eGFR between 30 and 45 mL/min/1.73 m2

Women who did not breastfeed may technically have more flexibility in timing, though most practitioners still recommend waiting until the six-week postpartum checkup at minimum

Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism

Weight gain can be caused by underlying medical conditions such as: Hypothyroidism PCOS Cushing syndrome Insulin resistance Diabetes Hormonal disorders An endocrinologist identifies these causes and develops a personalized treatment plan