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The approval was supported by the Phase III VISIBLE 2 study, where a statistically significant proportion of patients receiving 108 mg of Entyvio SC maintenance therapy administered every two weeks achieved long-term clinical remission compared to the placebo group after 52 weeks

We observed a change of 40% in plasma ascorbate from the second month and a leukocyte ascorbate change of 28% from the third month to the end of the study, respectively