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Its metabolite, quercetin (10 mg/kg, 50 mg/kg and 100 mg/kg), alleviated hydroquinone -induced vitiligo-like depigmentation in guinea pigs and promote melanosome recovery in a dose-dependent manner (Wang et al., 2025)

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A low-dose regimen (e.g., 1.2 mg initially, followed by 0.6 mg after 1 h) is recommended to minimize side effects such as diarrhea

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