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Trial registration UMIN000011118 (date of registration: July 4, 2013)

The gender breakdown within trial data shows particular promise for women

Recommendations for selenium intake Although we lack evidence that selenium supplementation results in clinical improvement in autoimmune thyroiditis (other than in mild Graves orbitopathy), it still makes sense to ensure that selenium intake is adequate, given the roles played by selenoproteins in human health ( Reference Rayman 100 ) and particularly in the thyroid ( Reference Schomburg 70 , Reference Schomburg and Kohrle 71 )

GSK-3-targeting fisetin promotes melanogenesis in B16F10 melanoma cells and Zebrafish larvae through -catenin activation