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Farin HF, Karthaus WR, Kujala P et al (2014) Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-

However, it is most often produced in the liver, in which the vital substance plays a central role

Collectively, this evidence strongly implicates the translocation and colonization of oral Streptococcus species within the gut as a key driver of dysbiosis contributing to diverse systemic pathologies