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The first report of a nuclear gene mutation causing a mitochondrial respiratory chain deficiency in humans was identified in two sisters presenting with developmental regression at 10 months of age, pyramidal tract signs, leukodystrophy with early demise, Complex II deficiency, and homozygous mutations (R554W) in the SDHA gene [122,123]

L., Huang, Y

For example, doctors warn that Foundayo may reduce the effectiveness of oral birth control during the first weeks of treatment or when the dose is increased, and it can also interact with certain drugs such as simvastatin, a cholesterollowering medication