Recommended by experts from the Endocrinology Department at Oxford University Hospitals and Diabetes UK
Gene variants on genes such as MTHFR encoding methylenetetrahydrofolate reductase, MTR encoding methionine synthase, MTRR encoding methionine synthase reductase and CBS encoding cystathionine-B synthase in the methylation pathway can lead to a decreased ability to create sufficient methyl donor (SAMe) and may lead to disruptions in the SAMe:SAH ratio, thus altering methylation capacity and epigenetic regulation
Laboratory studies often utilize GHK-Cu in cell culture systems (e.g., with fibroblasts, keratinocytes, or stem cells) or in animal models to elucidate its effects on cellular proliferation, differentiation, and ECM dynamics
Potential Benefits and Consequences of Keto With the keto diet, benefits observed over a 612-month period include short-term weight loss, improved insulin sensitivity, and decreased blood pressure (Batch et al., 2020)