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Featured Experts Rekha Kumar, MD is a board-certified endocrinologist in New York Eduardo Grunvald, MD is a board-certified internist and obesity specialist in San Diego Injectable GLP-1s: Wegovy, Zepbound and Other Weekly Shots Most GLP-1s currently approved for weight loss are administered weekly as subcutaneous injections with a prefilled pen

Severe injection site reactions : Mild soreness is normal, but increasing pain, significant swelling, or signs of infection (redness, warmth, discharge) require medical review

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Injectable GLP-1 medications generally reach higher peak plasma levels because of more complete bioavailability