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Description

In summary, Se deficiency appears to be a risk factor for HT and the current evidence does not justify the use of Se supplementation as part of the treatment of HT, despite its ability to improve immune function

Selenocysteine (Sec) is the substitution of Se for sulfur from cysteine, which can enhance the resistance of GPX4 to irreversible peroxidation and prevent hydroperoxide-induced ferroptosis [13, 31]