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But before assuming that a GLP-1 medication has stopped working, clinicians will typically consider how the patient is using the drug, such as whether it's being taken properly, with little to no missed doses, and whether it is being stored properly

Frequently asked questions Can I take my GLP-1 shot 12 hours early

When Ozempic significantly reduces appetite, and therefore meal frequency and food volume, the mechanical stimulation needed to maintain healthy salivary flow decreases