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Additionally, the American Society of Anesthesiologists has issued specific guidelines about discontinuing GLP-1 medications before surgery due to delayed gastric emptying concerns, which requires careful planning and medical supervision

Similarly, carnitine/acetyl-L-carnitine has been used in treatment of degenerative neuronal function in older Down's Syndrome patients since upon autopsy it was revealed that almost 100% of these patients over 40 years of age had symptoms of dementia [117]

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Semaglutide exerts several direct effects on digestive function, primarily through its action on GLP-1 receptors distributed throughout the gastrointestinal tract