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doi: 10.1210/en.2007-1292 Summary Keywords GLP-1, DPP-4, fracture, diabetes, bone, osteoporosis, antidiabetic, glucose-lowering drugs Citation Al-Mashhadi ZK, Viggers R, Fuglsang-Nielsen R, Vestergaard P, Gregersen S and Starup-Linde J (2022) The risk of major osteoporotic fractures with GLP-1 receptor agonists when compared to DPP-4 inhibitors: A Danish nationwide cohort study

Worsening of diabetic retinopathy has been observed primarily with semaglutide during rapid glycemic improvement, particularly in patients with pre-existing retinopathy

If you can, get bloodwork done (blood sugar and cholesterol levels)

This is more personalized than the traditional approach of recommending a treatment to a large group of people based on broad factors