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Antidiabetic drugs restore abnormal transport of amyloid- across the blood-brain barrier and memory impairment in db/db mice

doi: 10.1210/en.2013-1934, 120 QuastD

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But biologically the four are quite different molecules operating through distinct, only partly overlapping mechanisms: GHK-Cu (glycyl-L-histidyl-L-lysine plus copper) is a naturally occurring human tripeptide-copper complex, best characterized as a modulator of skin remodeling, collagen synthesis, and antioxidant gene expression