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Up to this point, we have ignored the fact that some drugs follow more complex multicompartment pharmacokinetics, eg, the distribution process illustrated by the two-compartment model in Figure 32

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These are amphiphilic lipid nanoparticles, allowing the inclusion of hydrophilic and hydrophobic substances [16]

The treatment with kimchi extract resulted in a notable upregulation of certain collagen genes, particularly COL1 A1, COL1 A2, COL7 A1, and COL17 A1, with the highest fold increases reaching up to approximately 3.6 for COL17 A1 in the cells treated with 5% kimchi extract