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Additionally, the gastrointestinal adverse effects commonly experienced with tirzepatideincluding nausea, vomiting, and reduced appetitemay lead to decreased dietary intake and potential nutritional deficiencies over time

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In the 1 mg Phase 2 arm, participants lost about 8% of body weight over 48 weeks

Last reviewed: June 9, 2026 Last updated: June 9, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations