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IDO-1 is found in various immune cells, including dendritic cells and macrophages, where it suppresses immune function by depleting tryptophan an amino acid vital for T-cell activity and generating immunosuppressive byproducts such as kynurenine

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Their antioxidant potential depends on the OH group due to their ability to donate H + [82] and capture unpaired electrons via the -electron system [83]