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Glutathione production by the #14 mutant was tested in YCK50D and media composed of 10% (v/v) molasses and varying CSL concentrations (0%, 5%, 10%, 15%, 20%, and 25% v/v)

However, there was no noticeable effect on the duration of the migraine attack or the intensity of the headache (109)

Additionally, the pocket normally occupied by the conserved phenylalanine residue of the TIN2 F-X-L-X-P motif was fully obstructed by a crystal contact with a TRF1 TRFH copy in an adjacent asymmetric unit, further limiting the possibility of obtaining XChem hits outside of the leucine pocket

This helps regulate blood sugar and reduces the risk of spikes